Biopharmaceutical pipelines are expanding rapidly, but many facilities are still relying on traditional “freezer farm” storage architectures built around dozens of distributed ultra-low temperature freezers.
While familiar, these setups introduce critical challenges:
• Inefficient use of valuable facility space
• Complex monitoring and operational oversight
• High energy consumption and escalating operating costs
• Increased operational risk as storage volumes grow
As advanced modalities such as biologics, cell & gene therapies, and high-value clinical materials continue to scale, legacy freezer farms often become a bottleneck to facility efficiency and long-term scalability.
A new architecture for ULT storage
In this webinar, we explore an alternative approach:
Centralized, large-scale ULT infrastructure purpose-built for modern biopharmaceutical facilities.
Drawing on real-world performance data from more than 220 installations worldwide, we examine when freezer farms stop scaling efficiently, and when centralized ULT infrastructure becomes the smarter architectural choice.
We will walk through the technical, operational and regulatory considerations that determine feasibility, including:
• Site & utility readiness (power density, backup power, building envelope, central plant capacity)
• Integration with existing facilities (labs, warehouses, material flows, gowning areas, airlocks and sample logistics)
• Regulatory and quality impact (GMP zoning, validation strategies, data integrity and change control)
• Storage model transformation (shifting from lab-owned freezers to a centralized ULT utility)
• Implementation strategy and risk mitigation (inventory migration, phased transition and freezer decommissioning without disrupting supply)
Real-world feasibility example
As an example, we will review a clinical campus operating 40+ ULT freezers that planned to double its cell and gene therapy trials.
A simple feasibility assessment revealed opportunities to:
• consolidate storage infrastructure
• reduce energy consumption by up to 60%
• strengthen redundancy and reliability
• implement a phased migration without disrupting clinical or commercial supply.
What you will learn
Participants will gain exclusive insight into the engineering design principles behind LOWENCO’s large-scale ULT storage infrastructure, including benchmark data comparing centralized systems with traditional freezer farms.
Key takeaway
Drawing on engineering insights and real-world performance data, this webinar will help you evaluate when centralized ULT infrastructure becomes the most scalable, resilient and cost-efficient strategy for supporting future biopharmaceutical growth.
Who should attend
This session is designed for professionals involved in:
• Biopharmaceutical facility design
• Infrastructure and utilities planning
• Engineering and technical operations
• Cold storage and product management
